Cardiac ion channel function in Duchenne Muscular Dystrophy, Sensory neuron ion channel function and novel drugs for treatment of chronic pain.

Australian Physiological Society, British Society for Cardiovascular Research

Click here to view complete Curriculum Vitae

Dr. Watson received a PhD from Monash University, Faculty of Medicine, Melbourne, Australia in 1995. He joined St. George’s University, School of Medicine, Department of Physiology and Neuroscience in 2009.

Over the last 8 years Dr. Watson has taught students studying Medicine, Nursing and Biomedical Science at the University of Queensland and University of Southern Queensland (USQ), Australia, and St. George’s University, Grenada, in the following areas: Neurophysiology, Respiratory Physiology, Cardiovascular Physiology, Renal Physiology, Pharmacology, and Muscle Physiology.

Prior to his arrival to St. George’s University, Dr. Watson was appointed as a Visiting Research Fellow within the University of Oxford, Department of Cardiovascular Medicine, John Radcliffe Hospital.

At present he is supervising a PhD student at the University of Southern Queensland in the dissertation: “Genetic alterations and treatments to improve cardiac muscle function in Duchene Muscular Dystrophy”

Laws N, Cornford-Nairn R, Irwin N, Watson M and Hoey A. (2008). The effects of long-term perindopril treatment on mdx mice. Muscle & Nerve, Submitted

M. Watson, E. Lee & A. Hoey. (2008). Contribution of Nitric Oxide to vagal nerve function in the dystrophin deficient heart. Muscle & Nerve, Submitted

Marrett G, Watson M, Woolf P, Laws N and Hoey A. (2008). The effect of aging and fibrosis on cardiac contractility and lusitropy in mdx hearts and isolated cardiac myocytes. Am J Physiol Heart Circ Physiol., Submitted

Woolf PJ, Lu S, Cornford-Nairn R, Watson M, Xiao XH, Holroyd SM, Brown L, Hoey AJ. (2006). Alterations in dihydropyridine receptors in dystrophin-deficient cardiac muscle. Am J Physiol Heart Circ Physiol, 290(6):H2439-45.

Nielsen K, Watson M, Adams D., Gage P, Hammarstrom A, Adams D, Thomas L, Hill J, Alewood P Craik D, Lewis R. (2002) Structure of µ-conotoxin PIIIA, a preferential inhibitor of persistent TTX-sensitive sodium channels. Journal Biol. Chem., 277(30) 27247-55.

Watson, M and Hoey A. Parent Project Muscular Dystrophy: Nitric Oxide Signalling in DMD (2006-2008).

Watson, M & Hoey, A. Parent Project Muscular Dystrophy: Inhibition of TGF beta signalling to improve cardiac function and fibrosis in DMD. (2006-2008).

Watson, M. Actions of synthetic conotoxins on sodium channels in sensory neurons. Early Career Researcher Program. (2002-2004)

Hoey A & Watson, M. Combined Antisense oligonucleotide and steroid treatments in DMD. Research Infrastructure Program (RIP)

Hoey, A, Learmonth, R, & Watson, M. Electrophysiology and Enhanced Fluorescence Suite. Research Infrastructure Program (RIP)

Watson, M, & Hoey, A. Advanced Electrophysiology Suite. Research Infrastructure Program (RIP)